Akathesia: A Tortured Restlessness

What is akathesia? It is a sensation of inner restlessness so bad it can increase the risk of suicide. Don't delay akathesia treatment.


There are particular side effects from medicine that physicians want to know right away if you have. Akathesia is one of them. Akathesia is a sensation of inner restlessness so bad that it can actually increase the risk of suicide. People suffering from it are unable to sit still and often describe it as a creepy-crawly sensation inside of them. Akathesia treatment usually works pretty quickly. Let’s go over what is akathesia to be sure you can recognize it in the unfortunate chance that you or someone you know experiences it.

How do you get akathesia?

Akathesia is a potential side effect on medications prescribed for psychiatric illness (there are other non-psychiatric medication that can cause it too although it is less common). It is seen most frequently with antipsychotic medications but also can be caused by antidepressant medications.


Akathesia is dose dependent which means the risk of it can be increased by raising the dose too quickly. When starting on medication, start with a low dose and raise it slowly to minimize this risk.

What symptoms does it cause? 

What is akathesia? It is a sensation of inner restlessness so bad it can increase the risk of suicide. Don't delay akathesia treatment.


A person experiencing akathesia may:


  • Unable to sit still
  • Restlessness
  • Feel fidgety,
  • Be rocking back and forth,
  • Pacing or marching in place,
  • Be irritable and tense,
  • panicked,
  • Agitated,
  • Unable to sleep.

Akathesia Treatment:

What is akathesia? It is a sensation of inner restlessness so bad it can increase the risk of suicide. Don't delay akathesia treatment.



It is important to know akathesia goes away. This isn’t a permanent state of torture! Also, we are generally able to manage this side-effect as an outpatient although depending on individual circumstances someone may require hospitalization.

First step:

The first step in akathesia treatment is often to discontinue or reduce the medication causing the restlessness. It can take a week or so for the medication levels to be lowered in the body so other treatments often need to be used to keep people comfortable while waiting.


There are several quick-acting medications used to alleviate akathesia. Generally, these akathesia treatments reduce the extreme restlessness pretty rapidly. Your physician may have to raise the dose of the medication if the initial amount wasn’t enough to minimize the symptoms.


There are several options for akathesia treatment medications but 2 commonly used examples are:

  • A blood pressure medication called propranolol (Inderal)
  • Clonazepam (Klonopin), an anti-anxiety medication.

Akathesia: In conclusion

Don’t let akathesia go untreated. If you ever had a justifiable reason to emergency page your doctor this is one of them. If you are unable to sit still, and have extreme restlessness after starting or raising a dose of your medication, contact your physician right away. Akathesia treatment can work quickly so don’t delay.


Other medication side effects not to miss:

Neuroleptic Malignant Syndrome: Rare but Potentially Deadly Side Effects of Antipsychotic Medications


What is Serotonin Syndrome? Hint: It’s an Emergency. Know the Signs and Symptoms of Serotonin Syndrome.


Take psychiatric medications? Be aware of SIADH hyponatremia and SIADH symptoms


Will You Have Antidepressant Withdrawal Symptoms?




Please follow and like us:

4 thoughts on “Akathesia: A Tortured Restlessness”

  1. Great information. Thank you for educating me about this topic. So important to recognise and treat early.

  2. how can a clinician understand the difference between akathesia and add? Or just anxiety or OC agitation? Thanks-

  3. Great questions- and this is why it is important to consult with your doctor if there is a question of akathesia. If it was ADHD it wouldn’t be a new sensation and should be quite distinguishable from akathesia. Akathesia causes feelings of anxiety and agitation but again one’s doctor would usually be able to distinguish the source of the symptoms- especially if it happens around the same time as a medication change.

Comments are closed.